Cervical cancer continues to be a major worldwide health concern and makes up about 12% of all the cancers in women. It is one of the major AIDS defining cancers in HIV positive women with an impact which is felt generally across the low and middle income countries. Increasingly high risk behaviour in young women puts them at risk for acquiring the germ called Human Papilloma virus (HPV) at a higher rate and this same high risk behaviour also predisposes them for HIV infection. In Botswana the rate is staggering and the need to address this dramatic infectious pandemic is dire. Many women in Botswana suffer with cervical cancer (cancer of the month of the womb) caused by HPV. This germ is very common. However, of the many women who get this infection only a few develop the cancer. This program is collaborative effort of a multidisciplinary team of researchers at the University of Botswana and the University of Pennsylvania.